Episode 07: In Search of a Cure

ACRONYMS OF CLINICAL TRIALS:

  • CAESAR: Canada, Australia, Europe, South Africa Aids Study
  • EPIC: European Prospective Investigation into Cancer and Nutrition
  • COOL AID: Cooling For Acute Ischemic Brain Damage
  • CHRISTMAS: Carvedilol Hibernating Reversible Ischaemia Trial
  • THUNDER: Taxan With Short Time For Contact For Reduction Of Restenosis In Distal Arteries
  • SYNERGY: Superior Yield Of The New Strategy Of Enoxaparin, Revascularization, And Glycoprotein IIb/IIia Inhibitors
  • TORPEDO - Thrombus Obliteration by Rapid Percutaneous Endovenous Intervention (PEVI) in Deep Venous Occlusion
  • BATMAN - Bisphosphonate and Anastrozole TrialBone Maintenance Algorithm Assessment
  • APRICOT: Antithrombotics In The Prevention Of Reocclusion In Coronary Thrombolysis
  • CAPRICORN: Carvedilol Post Infarct Survival Control in Left Ventricular Dysfunction Study
  • MAGIC: Myoblast Autologous Grafting In Ischemic Cardiomyopathy
  • RAVE: Regional Angiogenesis With Vascular Endothelial Growth Factor In Peripheral Arterial Disease

Also, Greek Gods are a popular choice, with studies named ATHENA, APOLLO, HERMES, ZEUS, and so on. There is an ADAM and EVE, as well as a study titled DEVIL.

Though most of these are proper acronyms in which, as acronyms should - each first letter is chosen, but - you may have noticed -  some did some magic with their abbreviations such as a study called VICTORY, which stands for "electiVe and acute stentIng of Coronary arTeries On ExpRess™ [coronary stent] sYstem”).

and a personal favorite of mine: A study titled: AWESOME: Angina With Extremely Serious Operative Mortality Evaluation.

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What was the most interesting thing we talked about? What was the least? How can we improve in future episodes?

Thank you, again, so much for listening! 

-Ania

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REFERENCES FOR EPISODE 07:

A service of the U.S. National Institutes of Health

www.clinicaltrials.gov 

https://clinicaltrials.gov/ct2/about-studies/learn

Discovery and Development of Penicillin

https://www.acs.org/content/acs/en/education/whatischemistry/landmarks/flemingpenicillin.html

Fletcher, Charles. "First clinical use of penicillin." British medical journal (Clinical research ed.) 289.6460 (1984): 1721.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1444782/pdf/bmjcred00533-0015.pdf

Bhatt, Arun. "Evolution of clinical research: a history before and beyond James Lind." Perspectives in clinical research 1.1 (2010): 6. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149409/

Clinical trial names can be quite AMUSING, but they don’t include unicorns

http://blogs.nature.com/spoonful/2010/09/clinical_trial_names_can_be_qu.html 

How Do Clinical Trials Work?

https://www.nhlbi.nih.gov/studies/clinicaltrials/work

Sertkaya, Aylin, et al. "Key cost drivers of pharmaceutical clinical trials in the United States." Clinical Trials 13.2 (2016): 117-126.

http://journals.sagepub.com/doi/full/10.1177/1740774515625964 

Unlucky 13: Top Clinical Trial Failures of 2016

http://www.genengnews.com/the-lists/unlucky-13-top-clinical-trial-failures-of-2016/77900787

Acronyms of Clinical Trial Names

http://www.wikidoc.org/index.php/Acronyms_of_Clinical_Trial_Names